4ETW

Structure of the Enzyme-ACP Substrate Gatekeeper Complex Required for Biotin Synthesis

Summary for 4ETW

Entry DOI	10.2210/pdb4etw/pdb
Descriptor	Pimelyl-[acyl-carrier protein] methyl ester esterase, Acyl carrier protein, methyl 7-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxoheptanoate, ... (4 entities in total)
Functional Keywords	esterase, hydrolase
Biological source	Shigella flexneri More
Total number of polymer chains	4
Total formula weight	77241.80
Authors	Agarwal, V.,Nair, S.K. (deposition date: 2012-04-24, release date: 2012-10-17, Last modification date: 2019-07-17)
Primary citation	Agarwal, V.,Lin, S.,Lukk, T.,Nair, S.K.,Cronan, J.E. Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proc.Natl.Acad.Sci.USA, 109:17406-17411, 2012 Cited by PubMed: 23045647 DOI: 10.1073/pnas.1207028109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation