4EM3
Crystal Structure of Staphylococcus aureus bound with the covalent inhibitor MeVS-CoA
Summary for 4EM3
Entry DOI | 10.2210/pdb4em3/pdb |
Related | 1YQZ 4EM4 4EMW 4EQR 4EQS 4EQW 4EQX |
Descriptor | Coenzyme A disulfide reductase, FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, ... (6 entities in total) |
Functional Keywords | oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor |
Biological source | Staphylococcus aureus subsp. aureus |
Total number of polymer chains | 2 |
Total formula weight | 102072.20 |
Authors | Wallace, B.D.,Edwards, J.S.,Claiborne, A.,Redinbo, M.R. (deposition date: 2012-04-11, release date: 2012-10-17, Last modification date: 2017-11-15) |
Primary citation | Wallace, B.D.,Edwards, J.S.,Wallen, J.R.,Moolman, W.J.,van der Westhuyzen, R.,Strauss, E.,Redinbo, M.R.,Claiborne, A. Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural Insights. Biochemistry, 51:7699-7711, 2012 Cited by PubMed: 22954034DOI: 10.1021/bi301026c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.977 Å) |
Structure validation
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