Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003756 | molecular_function | protein disulfide isomerase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0050661 | molecular_function | NADP binding |
| B | 0003756 | molecular_function | protein disulfide isomerase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050451 | molecular_function | CoA-disulfide reductase (NADPH) activity |
| B | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| B | 0050661 | molecular_function | NADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 38 |
| Details | BINDING SITE FOR RESIDUE FAD A 501 |
| Chain | Residue |
| A | VAL7 |
| A | ASN42 |
| A | CYS43 |
| A | HIS79 |
| A | VAL81 |
| A | SER112 |
| A | PRO113 |
| A | GLY114 |
| A | ARG131 |
| A | TYR158 |
| A | VAL159 |
| A | GLY8 |
| A | PHE245 |
| A | GLY276 |
| A | ASP277 |
| A | PRO293 |
| A | LEU294 |
| A | ALA295 |
| A | CA6507 |
| A | HOH605 |
| A | HOH607 |
| A | HOH620 |
| A | VAL10 |
| A | HOH626 |
| A | HOH651 |
| A | HOH727 |
| A | HOH736 |
| A | HOH834 |
| A | HOH835 |
| B | TYR419 |
| B | ALA420 |
| B | PRO421 |
| A | ALA11 |
| A | GLY12 |
| A | PHE32 |
| A | GLU33 |
| A | LYS34 |
| A | ASP35 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 502 |
| Chain | Residue |
| A | GLU54 |
| A | HOH734 |
| A | HOH769 |
| A | HOH1001 |
| A | HOH1030 |
| A | HOH1048 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MG A 503 |
| Chain | Residue |
| A | HOH731 |
| A | HOH958 |
| A | HOH994 |
| B | HOH805 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL A 504 |
| site_id | AC5 |
| Number of Residues | 23 |
| Details | BINDING SITE FOR RESIDUE CA6 A 507 |
| Chain | Residue |
| A | VAL10 |
| A | ALA14 |
| A | THR15 |
| A | SER18 |
| A | GLN19 |
| A | ARG22 |
| A | SER39 |
| A | PHE40 |
| A | ALA41 |
| A | ASN42 |
| A | CYS43 |
| A | ALA44 |
| A | LYS71 |
| A | HIS299 |
| A | FAD501 |
| A | HOH688 |
| A | HOH851 |
| A | HOH890 |
| B | TYR361 |
| B | TYR419 |
| B | LYS427 |
| B | MET432 |
| B | TYR435 |
| site_id | AC6 |
| Number of Residues | 40 |
| Details | BINDING SITE FOR RESIDUE FAD B 501 |
| Chain | Residue |
| B | ALA295 |
| B | CA6509 |
| B | HOH608 |
| B | HOH610 |
| B | HOH619 |
| B | HOH638 |
| B | HOH656 |
| B | HOH685 |
| B | HOH695 |
| B | HOH804 |
| B | HOH815 |
| B | HOH835 |
| B | HOH1025 |
| A | TYR419 |
| A | ALA420 |
| A | PRO421 |
| B | VAL7 |
| B | GLY8 |
| B | VAL10 |
| B | ALA11 |
| B | GLY12 |
| B | PHE32 |
| B | GLU33 |
| B | LYS34 |
| B | ASP35 |
| B | ASN42 |
| B | CYS43 |
| B | HIS79 |
| B | GLU80 |
| B | VAL81 |
| B | SER112 |
| B | PRO113 |
| B | GLY114 |
| B | ARG131 |
| B | ASN242 |
| B | PHE245 |
| B | GLY276 |
| B | ASP277 |
| B | PRO293 |
| B | LEU294 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 502 |
| Chain | Residue |
| B | HOH601 |
| B | HOH602 |
| B | HOH603 |
| B | HOH604 |
| B | HOH605 |
| B | HOH952 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B 503 |
| Chain | Residue |
| B | HOH715 |
| B | HOH809 |
| B | HOH949 |
| B | HOH950 |
| B | HOH986 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 508 |
| site_id | BC1 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE CA6 B 509 |
| Chain | Residue |
| A | TYR361 |
| A | TYR419 |
| A | LYS427 |
| A | MET432 |
| A | TYR435 |
| B | VAL10 |
| B | ALA11 |
| B | ALA14 |
| B | THR15 |
| B | SER18 |
| B | GLN19 |
| B | ARG22 |
| B | SER39 |
| B | PHE40 |
| B | ALA41 |
| B | ASN42 |
| B | CYS43 |
| B | ALA44 |
| B | LYS71 |
| B | ALA295 |
| B | HIS299 |
| B | FAD501 |
| B | HOH890 |
| B | HOH898 |
| B | HOH989 |
| B | HOH995 |
| B | HOH1004 |
| B | HOH1029 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Redox-active","evidences":[{"source":"HAMAP-Rule","id":"MF_01608","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 118 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01608","evidenceCode":"ECO:0000255"}]} |
