4EGC
Crystal Structure of MBP-fused Human Six1 Bound to Human Eya2 Eya Domain
Summary for 4EGC
Entry DOI | 10.2210/pdb4egc/pdb |
Related PRD ID | PRD_900001 |
Descriptor | Maltose-binding periplasmic protein, Homeobox protein SIX1 chimera, Eyes absent homolog 2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | homeodomain (hd), six domain (sd), eya domain (ed), haloacid dehalogenase (had), transcription factor, co-activator, protein phosphatase, dna binding, fusion protein, nucleus, transcription-hydrolase complex, transcription/hydrolase |
Biological source | Escherichia coli (human) More |
Total number of polymer chains | 2 |
Total formula weight | 95895.95 |
Authors | Zhao, R.,Patrick, A.N. (deposition date: 2012-03-30, release date: 2013-02-27, Last modification date: 2024-02-28) |
Primary citation | Patrick, A.N.,Cabrera, J.H.,Smith, A.L.,Chen, X.S.,Ford, H.L.,Zhao, R. Structure-function analyses of the human SIX1-EYA2 complex reveal insights into metastasis and BOR syndrome. Nat.Struct.Mol.Biol., 20:447-453, 2013 Cited by PubMed: 23435380DOI: 10.1038/nsmb.2505 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.994 Å) |
Structure validation
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