4EC3
Structure of berberine bridge enzyme, H174A variant in complex with (S)-reticuline
Summary for 4EC3
Entry DOI | 10.2210/pdb4ec3/pdb |
Related | 3D2D 3D2J 3FW7 3FW8 |
Descriptor | Reticuline oxidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... (7 entities in total) |
Functional Keywords | p-cresol methyl hydroxylase superfamily, oxidoreductase, fad, bi-covalent flavinylation |
Biological source | Eschscholzia californica (California poppy) |
Cellular location | Cytoplasmic vesicle: P30986 |
Total number of polymer chains | 1 |
Total formula weight | 60252.82 |
Authors | Winkler, A.,Macheroux, P.,Gruber, K. (deposition date: 2012-03-26, release date: 2012-07-18, Last modification date: 2023-09-13) |
Primary citation | Wallner, S.,Winkler, A.,Riedl, S.,Dully, C.,Horvath, S.,Gruber, K.,Macheroux, P. Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme. Biochemistry, 51:6139-6147, 2012 Cited by PubMed: 22757961DOI: 10.1021/bi300411n PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6501 Å) |
Structure validation
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