4EC3
Structure of berberine bridge enzyme, H174A variant in complex with (S)-reticuline
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009820 | biological_process | alkaloid metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0050468 | molecular_function | reticuline oxidase activity |
| A | 0050660 | molecular_function | flavin adenine dinucleotide binding |
| A | 0071949 | molecular_function | FAD binding |
Functional Information from PROSITE/UniProt
| site_id | PS00862 |
| Number of Residues | 34 |
| Details | OX2_COVAL_FAD Oxygen oxidoreductases covalent FAD-binding site. PsaiilpgSkeELsntIrcirkgswt...IrlrSGGH |
| Chain | Residue | Details |
| A | PRO71-HIS104 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 174 |
| Details | Domain: {"description":"FAD-binding PCMH-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00718","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16728404","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19457868","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19457868","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Cross-link: {"description":"6-(S-cysteinyl)-8alpha-(pros-histidyl)-FAD (His-Cys)","evidences":[{"source":"PubMed","id":"16728404","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19457868","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
