4E3B

Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide

Summary for 4E3B

Entry DOI	10.2210/pdb4e3b/pdb
Related	3SFJ 4E34 4E35
Descriptor	Tax1-binding protein 3, iCAL50 peptide (3 entities in total)
Functional Keywords	pdz-peptide complex, signaling protein-protein binding complex, signaling protein/protein binding
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: O14907
Total number of polymer chains	4
Total formula weight	25040.41
Authors	Amacher, J.F.,Madden, D.R. (deposition date: 2012-03-09, release date: 2012-12-26, Last modification date: 2023-09-13)
Primary citation	Amacher, J.F.,Cushing, P.R.,Bahl, C.D.,Beck, T.,Madden, D.R. Stereochemical Determinants of C-terminal Specificity in PDZ Peptide-binding Domains: A NOVEL CONTRIBUTION OF THE CARBOXYLATE-BINDING LOOP. J.Biol.Chem., 288:5114-5126, 2013 Cited by PubMed: 23243314 DOI: 10.1074/jbc.M112.401588 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.5 Å)

Structure validation