4E3B
Crystal structure of Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to iCAL36-L (ANSRWPTSIL) peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR CHAIN C OF ICAL50 PEPTIDE |
| Chain | Residue |
| A | ILE29 |
| A | ASP41 |
| A | GLN44 |
| A | ASN45 |
| A | THR59 |
| A | ARG60 |
| A | HIS91 |
| A | ARG95 |
| A | LEU98 |
| A | HOH215 |
| A | HOH224 |
| A | LEU30 |
| A | HOH296 |
| C | HOH101 |
| C | HOH102 |
| C | HOH103 |
| C | HOH104 |
| C | HOH107 |
| C | HOH108 |
| C | HOH109 |
| C | HOH110 |
| C | HOH111 |
| A | GLY31 |
| C | HOH112 |
| C | HOH113 |
| C | HOH114 |
| A | PHE32 |
| A | SER33 |
| A | ILE34 |
| A | GLY35 |
| A | GLY36 |
| A | GLN40 |
| site_id | AC2 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR CHAIN D OF ICAL50 PEPTIDE |
| Chain | Residue |
| B | ILE29 |
| B | LEU30 |
| B | GLY31 |
| B | PHE32 |
| B | SER33 |
| B | ILE34 |
| B | GLY35 |
| B | GLY36 |
| B | GLN40 |
| B | ASP41 |
| B | GLN44 |
| B | ASN45 |
| B | ASP50 |
| B | THR59 |
| B | ARG60 |
| B | HIS91 |
| B | ARG95 |
| B | LEU98 |
| B | HOH215 |
| B | HOH273 |
| D | HOH101 |
| D | HOH102 |
| D | HOH103 |
| D | HOH104 |
| D | HOH105 |
| D | HOH106 |
| D | HOH107 |
| D | HOH108 |
| D | HOH110 |
| D | HOH111 |
| D | HOH112 |
| D | HOH113 |
| D | HOH116 |
| D | HOH117 |
| D | HOH118 |
| D | HOH119 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 194 |
| Details | Domain: {"description":"PDZ","evidences":[{"source":"PROSITE-ProRule","id":"PRU00143","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
