4E2F

Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state

Summary for 4E2F

Entry DOI	10.2210/pdb4e2f/pdb
Related	1D09 1ZA1
Descriptor	Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION, ... (4 entities in total)
Functional Keywords	transferase, cooperativity, allosteric transition, intermediate, transferase-protein binding complex, transferase/protein binding
Biological source	Escherichia coli More
Total number of polymer chains	12
Total formula weight	309276.83
Authors	Guo, W.,Kantrowitz, E.R. (deposition date: 2012-03-08, release date: 2012-05-02, Last modification date: 2024-02-28)
Primary citation	Guo, W.,West, J.M.,Dutton, A.S.,Tsuruta, H.,Kantrowitz, E.R. Trapping and structure determination of an intermediate in the allosteric transition of aspartate transcarbamoylase. Proc.Natl.Acad.Sci.USA, 109:7741-7746, 2012 Cited by PubMed: 22547808 DOI: 10.1073/pnas.1119683109 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation