4E2F
Crystal Structure of E. coli Aspartate Transcarbamoylase K164E/E239K Mutant in an intermediate state
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (I, K, G, C, A...) | Aspartate carbamoyltransferase catalytic chain | polymer | 310 | 34337.1 | 6 | UniProt (P0A786) Pfam (PF02729) Pfam (PF00185) | Escherichia coli | Aspartate transcarbamylase, ATCase |
| 2 | F, G, I, J, K... (D, B, J, L, H...) | Aspartate carbamoyltransferase regulatory chain | polymer | 153 | 17143.6 | 6 | UniProt (P0A7F3) Pfam (PF01948) Pfam (PF02748) | Escherichia coli | |
| 3 | M, N, O, P, Q... (D, B, J, L, H...) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 4 | AA, BA, CA, DA, S... (J, L, H, F, I...) | water | water | 18.0 | 506 | Chemie (HOH) |
Sequence modifications
I, K, G, C, A, E: 1 - 310 (UniProt: P0A786)
| PDB | External Database | Details |
|---|---|---|
| Glu 164 | Lys 165 | engineered mutation |
| Lys 239 | Glu 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 308884.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 392.5 | |
| All* | Total formula weight | 309276.8 |
