4DSY

Crystal structure of red kidney bean purple acid phosphatase in complex with Maybridge fragment CC24201

Summary for 4DSY

Entry DOI	10.2210/pdb4dsy/pdb
Related	4DHL
Descriptor	Purple acid phosphatase, 1,2-ETHANEDIOL, ACETATE ION, ... (12 entities in total)
Functional Keywords	phosphatase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Phaseolus vulgaris (French bean,kidney bean,string bean)
Total number of polymer chains	4
Total formula weight	207809.08
Authors	Feder, D.,Hussein, W.M.,Clayton, D.J.,Kan, M.,Schenk, G.,McGeary, R.P.,Guddat, L.W. (deposition date: 2012-02-20, release date: 2012-09-19, Last modification date: 2020-07-29)
Primary citation	Feder, D.,Hussein, W.M.,Clayton, D.J.,Kan, M.W.,Schenk, G.,McGeary, R.P.,Guddat, L.W. Identification of purple acid phosphatase inhibitors by fragment-based screening: promising new leads for osteoporosis therapeutics. Chem.Biol.Drug Des., 80:665-674, 2012 Cited by PubMed: 22943065 DOI: 10.1111/cbdd.12001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation