4DKV
Crystal structure of clade A/E 93TH057 HIV-1 gp120 core in complex with NBD-10007
Summary for 4DKV
Entry DOI | 10.2210/pdb4dkv/pdb |
Related | 4DKU |
Descriptor | HIV-1 gp120 core, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | hiv-1 gp120, clade a/e, cd4 mimic, nbd-10007, hydrolase |
Biological source | Human immunodeficiency virus 1 More |
Total number of polymer chains | 2 |
Total formula weight | 84095.42 |
Authors | Kwon, Y.D.,Debnath, A.K.,Kwong, P.D. (deposition date: 2012-02-04, release date: 2013-03-20, Last modification date: 2023-09-13) |
Primary citation | Curreli, F.,Kwon, Y.D.,Zhang, H.,Yang, Y.,Scacalossi, D.,Kwong, P.D.,Debnath, A.K. Binding mode characterization of NBD series CD4-mimetic HIV-1 entry inhibitors by X-ray structure and resistance study. Antimicrob. Agents Chemother., 58:5478-5491, 2014 Cited by PubMed: 25001301DOI: 10.1128/AAC.03339-14 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1847 Å) |
Structure validation
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