4DJC
1.35 A crystal structure of the NaV1.5 DIII-IV-Ca/CaM complex
Summary for 4DJC
Entry DOI | 10.2210/pdb4djc/pdb |
Descriptor | Calmodulin, Sodium channel protein type 5 subunit alpha, CALCIUM ION, ... (5 entities in total) |
Functional Keywords | ef-hand, calcium-binding protein |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane ; Multi-pass membrane protein : Q14524 |
Total number of polymer chains | 2 |
Total formula weight | 21947.88 |
Authors | Sarhan, M.F.,Tung, C.-C.,Van Petegem, F.,Ahern, C.A. (deposition date: 2012-02-01, release date: 2012-02-22, Last modification date: 2024-02-28) |
Primary citation | Sarhan, M.F.,Tung, C.C.,Van Petegem, F.,Ahern, C.A. Crystallographic basis for calcium regulation of sodium channels. Proc.Natl.Acad.Sci.USA, 109:3558-3563, 2012 Cited by PubMed: 22331908DOI: 10.1073/pnas.1114748109 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.35 Å) |
Structure validation
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