4DGI
Structure of POM1 FAB fragment complexed with human PrPc Fragment 120-230
Summary for 4DGI
Entry DOI | 10.2210/pdb4dgi/pdb |
Related | 1TQB 2W9E |
Descriptor | Major prion protein, POM1 Fab Heavy chain, POM1 Fab Light chain, ... (5 entities in total) |
Functional Keywords | prion, antibody, protein binding |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Lipid-anchor, GPI-anchor. Isoform 2: Cytoplasm: P04156 |
Total number of polymer chains | 3 |
Total formula weight | 60017.31 |
Authors | Baral, P.K.,Wieland, B.,Swayampakula, M.,James, M.N. (deposition date: 2012-01-26, release date: 2012-10-31, Last modification date: 2013-01-23) |
Primary citation | Baral, P.K.,Wieland, B.,Swayampakula, M.,Polymenidou, M.,Rahman, M.H.,Kav, N.N.,Aguzzi, A.,James, M.N. Structural studies on the folded domain of the human prion protein bound to the Fab fragment of the antibody POM1. Acta Crystallogr.,Sect.D, 68:1501-1512, 2012 Cited by PubMed: 23090399DOI: 10.1107/S0907444912037328 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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