4DGE

TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant, HIV-1 CA(O-loop) complex

Summary for 4DGE

Entry DOI	10.2210/pdb4dge/pdb
Related	4DGA 4DGB 4DGC 4DGD
Descriptor	TRIMCyp, capsid protein (3 entities in total)
Functional Keywords	anti-viral protein, isomerase-viral protein complex, isomerase/viral protein
Biological source	Macaca mulatta (rhesus macaque) More
Cellular location	Capsid protein p24: Virion (By similarity). Matrix protein p17: Virion (By similarity). Nucleocapsid protein p7: Virion (By similarity): Q72497
Total number of polymer chains	4
Total formula weight	68322.10
Authors	Caines, M.E.C.,Bichel, K.,Price, A.J.,McEwan, W.A.,James, L.C. (deposition date: 2012-01-25, release date: 2012-02-08, Last modification date: 2023-09-13)
Primary citation	Caines, M.E.,Bichel, K.,Price, A.J.,McEwan, W.A.,Towers, G.J.,Willett, B.J.,Freund, S.M.,James, L.C. Diverse HIV viruses are targeted by a conformationally dynamic antiviral. Nat.Struct.Mol.Biol., 19:411-416, 2012 Cited by PubMed: 22407016 DOI: 10.1038/nsmb.2253 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation