4DGC

TRIMCyp cyclophilin domain from Macaca mulatta: cyclosporin A complex

Summary for 4DGC

• Entry DOI: 10.2210/pdb4dgc/pdb
• Related: 4DGA 4DGB 4DGD 4DGE
• Related PRD ID: PRD_000142
• Descriptor: TRIMCyp, cyclosporin A (3 entities in total)
• Functional Keywords: anti-viral protein, isomerase-immunosuppressant complex, isomerase/immunosuppressant
• Biological source: Macaca mulatta (rhesus macaque); More
• Total number of polymer chains: 10
• Total formula weight: 96185.49

Authors

Caines, M.E.C.,Bichel, K.,Price, A.J.,McEwan, W.A.,James, L.C. (deposition date: 2012-01-25, release date: 2012-02-08, Last modification date: 2023-12-06)

• Primary citation: Caines, M.E.,Bichel, K.,Price, A.J.,McEwan, W.A.,Towers, G.J.,Willett, B.J.,Freund, S.M.,James, L.C.; Diverse HIV viruses are targeted by a conformationally dynamic antiviral.; Nat.Struct.Mol.Biol., 19:411-416, 2012; PubMed: 22407016; DOI: 10.1038/nsmb.2253

Experimental method

X-RAY DIFFRACTION (2.65 Å)