4DGE
TRIMCyp cyclophilin domain from Macaca mulatta: H70C mutant, HIV-1 CA(O-loop) complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | TRIMCyp | polymer | 165 | 17981.5 | 2 | UniProt (B0LJC8) Pfam (PF00160) UniProt (by SIFTS) (P62940) | Macaca mulatta (rhesus macaque) | Peptidyl-prolyl cis-trans isomerase |
| 2 | C, D (C, D) | capsid protein | polymer | 146 | 16179.6 | 2 | UniProt (Q72497) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 (HIV-1) | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 200 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 165 (UniProt: B0LJC8)
C, D: 1 - 145 (UniProt: Q72497)
| PDB | External Database | Details |
|---|---|---|
| Cys 70 | His 373 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| Thr 83 | Leu 215 | engineered mutation |
| Pro 86 | Val 218 | engineered mutation |
| Ala 87 | His 219 | engineered mutation |
| Met 88 | Ala 220 | engineered mutation |
| Leu 91 | Ile 223 | engineered mutation |
| Pro 92 | Ala 224 | engineered mutation |
| Ile 96 | Met 228 | engineered mutation |
| Thr 100 | Arg 232 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68322.1 | |
| All* | Total formula weight | 68322.1 |
