4DBZ

Crystal Structure of V151L Actinorhodin Polyketide Ketoreductase with NADPH

Summary for 4DBZ

Entry DOI	10.2210/pdb4dbz/pdb
Related	4DC0 4DC1
Descriptor	Ketoacyl reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (3 entities in total)
Functional Keywords	rossmann fold, ketoreductase, oxidoreductase
Biological source	Streptomyces coelicolor
Total number of polymer chains	2
Total formula weight	60447.62
Authors	Javidpour, P.,Tsai, S.-C. (deposition date: 2012-01-16, release date: 2013-01-16, Last modification date: 2024-02-28)
Primary citation	Javidpour, P.,Bruegger, J.,Srithahan, S.,Korman, T.P.,Crump, M.P.,Crosby, J.,Burkart, M.D.,Tsai, S.C. The Determinants of Activity and Specificity in Actinorhodin Type II Polyketide Ketoreductase. Chem.Biol., 20:1225-1234, 2013 Cited by PubMed: 24035284 DOI: 10.1016/j.chembiol.2013.07.016 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.643 Å)

Structure validation