4CY7

Crystal structure of human insulin analogue (NMe-AlaB8)-insulin crystal form II

Summary for 4CY7
Related4CXL 4CXN
DescriptorINSULIN A CHAIN, INSULIN B CHAIN, SULFATE ION, ... (5 entities in total)
Functional Keywordshormone, diabetes
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains4
Total formula weight11846.51
Authors
Kosinova, L.,Veverka, V.,Novotna, P.,Collinsova, M.,Urbanova, M.,Jiracek, J.,Moody, N.R.,Turkenburg, J.P.,Brzozowski, A.M.,Zakova, L. (deposition date: 2014-04-10, release date: 2014-05-28, Last modification date: 2014-06-18)
Primary citationBrzozowski, A.M.,Collinsova, M.,Jiracek, J.,Kosinova, L.,Moody, N.R.,Novotna, P.,Turkenburg, J.P.,Urbanova, M.,Veverka, V.,Zakova, L.
An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53:3392-, 2014
PubMed: 24819248
DOI: 110.1021/BI500073Z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.4 Å)
Structure validation
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PDB entries from 2021-06-23