4CXL

Human insulin analogue (D-ProB8)-insulin

Summary for 4CXL
Related4CXN
DescriptorINSULIN A CHAIN, INSULIN B CHAIN, CHLORIDE ION, ... (4 entities in total)
Functional Keywordshormone, diabetes
Biological sourceHOMO SAPIENS (HUMAN)
More
Cellular locationSecreted: P01308 P01308
Total number of polymer chains2
Total formula weight5893.17
Authors
Kosinova, L.,Veverka, V.,Novotna, P.,Collinsova, M.,Urbanova, M.,Jiracek, J.,Moody, N.R.,Turkenburg, J.P.,Brzozowski, A.M.,Zakova, L. (deposition date: 2014-04-07, release date: 2014-05-28, Last modification date: 2014-06-18)
Primary citationBrzozowski, A.M.,Collinsova, M.,Jiracek, J.,Kosinova, L.,Moody, N.R.,Novotna, P.,Turkenburg, J.P.,Urbanova, M.,Veverka, V.,Zakova, L.
An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin.
Biochemistry, 53:3392-, 2014
PubMed: 24819248
DOI: 110.1021/BI500073Z
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation
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PDB entries from 2021-06-16