4CSJ
The discovery of potent selective glucocorticoid receptor modulators, suitable for inhalation
Summary for 4CSJ
Entry DOI | 10.2210/pdb4csj/pdb |
Descriptor | GLUCOCORTICOID RECEPTOR, NUCLEAR RECEPTOR COACTIVATOR 2, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | signaling protein, nuclear hormone receptor, ligand complex, peptide complex |
Biological source | HOMO SAPIENS (HUMAN) More |
Cellular location | Cytoplasm. Isoform Beta: Nucleus: P04150 |
Total number of polymer chains | 2 |
Total formula weight | 34295.53 |
Authors | Edman, K.,Ahlgren, R.,Bengtsson, M.,Bladh, H.,Backstrom, S.,Dahmen, J.,Henriksson, K.,Hillertz, P.,Hulikal, V.,Jerre, A.,Kinchin, L.,Kase, C.,Lepisto, M.,Mile, I.,Nilsson, S.,Smailagic, A.,Taylor, J.,Tjornebo, A.,Wissler, L.,Hansson, T. (deposition date: 2014-03-07, release date: 2014-05-07, Last modification date: 2023-12-20) |
Primary citation | Edman, K.,Ahlgren, R.,Bengtsson, M.,Bladh, H.,Backstrom, S.,Dahmen, J.,Henriksson, K.,Hillertz, P.,Hulikal, V.,Jerre, A.,Kinchin, L.,Kase, C.,Lepisto, M.,Mile, I.,Nilsson, S.,Smailagic, A.,Taylor, J.,Tjornebo, A.,Wissler, L.,Hansson, T. The Discovery of Potent and Selective Non-Steroidal Glucocorticoid Receptor Modulators, Suitable for Inhalation. Bioorg.Med.Chem.Lett., 24:2571-, 2014 Cited by PubMed: 24755427DOI: 10.1016/J.BMCL.2014.03.070 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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