4CNM
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
Summary for 4CNM
Entry DOI | 10.2210/pdb4cnm/pdb |
Related | 4CNC |
Descriptor | TROPHOBLAST GLYCOPROTEIN, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | cell adhesion, waif1, tpbg, trovax, mva-5t4, cancer, signaling, leucine-rich repeats, wnt/beta-catenin signaling pathway |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Membrane; Single-pass type I membrane protein (Potential): Q13641 |
Total number of polymer chains | 1 |
Total formula weight | 34932.35 |
Authors | Zhao, Y.,Malinauskas, T.,Harlos, K.,Jones, E.Y. (deposition date: 2014-01-23, release date: 2014-02-26, Last modification date: 2023-12-20) |
Primary citation | Zhao, Y.,Malinauskas, T.,Harlos, K.,Jones, E.Y. Structural Insights Into the Inhibition of Wnt Signaling by Cancer Antigen 5T4/Wnt-Activated Inhibitory Factor 1. Structure, 22:612-, 2014 Cited by PubMed: 24582434DOI: 10.1016/J.STR.2014.01.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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