4CNM
Crystal structure of human 5T4 (Wnt-activated inhibitory factor 1, Trophoblast glycoprotein)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | TROPHOBLAST GLYCOPROTEIN | polymer | 299 | 32900.4 | 1 | UniProt (Q13641) Pfam (PF01462) Pfam (PF13855) Pfam (PF01463) In PDB | HOMO SAPIENS (HUMAN) | 5T4 ONCOFETAL ANTIGEN, WNT-ACTIVATED INHIBITORY FACTOR, 5T4 ONCOFETAL TROPHOBLAST GLYCOPROTEIN, 5T4 ONCOTROPHOBLAST GLYCOPROTEIN, M6P1 |
| 2 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 4 | A | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 5 | Chemie (PEG) | |||
| 5 | A | CITRIC ACID | non-polymer | 192.1 | 1 | Chemie (CIT) | |||
| 6 | water | water | 18.0 | 124 | Chemie (HOH) |
Sequence modifications
A: 60 - 345 (UniProt: Q13641)
| PDB | External Database | Details |
|---|---|---|
| Glu 57 | - | expression tag |
| Thr 58 | - | expression tag |
| Gly 59 | - | expression tag |
| Gly 346 | - | expression tag |
| Thr 347 | - | expression tag |
| Glu 348 | - | expression tag |
| Thr 349 | - | expression tag |
| Ser 350 | - | expression tag |
| Gln 351 | - | expression tag |
| Val 352 | - | expression tag |
| Ala 353 | - | expression tag |
| Pro 354 | - | expression tag |
| Ala 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32900.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1607.6 | |
| All* | Total formula weight | 34932.4 |
