4CN2

Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element

Summary for 4CN2

• Entry DOI: 10.2210/pdb4cn2/pdb
• Related: 4CN3 4CN5 4CN7
• Descriptor: 5'-D(*TP*GP*AP*GP*TP*TP*CP*AP*AP*GP*GP*GP*TP*DC *AP*AP*TP)-3', 5'-D(*AP*TP*TP*GP*AP*CP*CP*CP*TP*TP*GP*AP*AP*DC *TP*CP*AP)-3', RETINOIC ACID RECEPTOR RXR-ALPHA, ... (8 entities in total)
• Functional Keywords: transcription-dna complex, nuclear receptor, transcription/dna
• Biological source: HOMO SAPIENS (HUMAN); More
• Cellular location: Nucleus : 4CN2
• Total number of polymer chains: 4
• Total formula weight: 31707.47

Authors

McEwen, A.G.,Poussin-Courmontagne, P.,Osz, J.,Rochel, N. (deposition date: 2014-01-21, release date: 2015-02-18, Last modification date: 2023-12-20)

• Primary citation: Osz, J.,Mcewen, A.G.,Poussin-Courmontagne, P.,Moutier, E.,Birck, C.,Davidson, I.,Moras, D.,Rochel, N.; Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor.; Sci.Rep., 5:8216-, 2015; PubMed: 25645674; DOI: 10.1038/SREP08216

Experimental method

X-RAY DIFFRACTION (2.069 Å)