4AWN
Structure of recombinant human DNase I (rhDNaseI) in complex with Magnesium and Phosphate.
Summary for 4AWN
Entry DOI | 10.2210/pdb4awn/pdb |
Descriptor | DEOXYRIBONUCLEASE-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (8 entities in total) |
Functional Keywords | hydrolase, endonuclease, pulmozyme |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 30332.16 |
Authors | Parsiegla, G.,Noguere, C.,Santell, L.,Lazarus, R.A.,Bourne, Y. (deposition date: 2012-06-04, release date: 2013-01-09, Last modification date: 2024-10-09) |
Primary citation | Parsiegla, G.,Noguere, C.,Santell, L.,Lazarus, R.A.,Bourne, Y. The Structure of Human DNase I Bound to Magnesium and Phosphate Ions Points to a Catalytic Mechanism Common to Members of the DNase I-Like Superfamily. Biochemistry, 51:10250-, 2012 Cited by PubMed: 23215638DOI: 10.1021/BI300873F PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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