46GH

Crystal structure of a de novo-designed VHH targeting BHRF1

Summary for 46GH

• Entry DOI: 10.2210/pdb46gh/pdb
• Descriptor: Apoptosis regulator BHRF1, BHRF1_VHH-N13 (2 entities in total)
• Functional Keywords: bhrf1, ppiflow, designed vhh, de novo protein
• Biological source: Epstein-barr virus strain ag876; More
• Total number of polymer chains: 20
• Total formula weight: 327096.81

Authors

Wang, S.,Yu, Q.L.,Tian, B.H.,Qin, X.Y.,Chen, M.C. (deposition date: 2026-09-21, release date: 2026-10-28)

• Primary citation: Yu, Q.L.,Guo, L.Y.,Qin, X.Y.,Huang, X.K.,Tian, B.H.,Wang, H.Z.,Liu, Y.,Wang, S.,Lang, Y.Z.,Shen, Z.H.Y.,Lin, J.,Chen, M.C.; High-Affinity Protein Binder Design via Flow Matching and In Silico Maturation; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.4 Å)