46GH
Crystal structure of a de novo-designed VHH targeting BHRF1
Functional Information from PROSITE/UniProt
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIhqqGGWStLI |
| Chain | Residue | Details |
| A | TRP143-ILE154 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 683 |
| Details | Region: {"description":"Interaction with host VRK2","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 200 |
| Details | Motif: {"description":"BH1"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 150 |
| Details | Motif: {"description":"BH2"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 20 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
