45IM

Cryo-EM structure of the outwardly rectifying potassium channel TOK1 from Saccharomyces cerevisiae in a lipid nanodisc

Summary for 45IM

• Entry DOI: 10.2210/pdb45im/pdb
• EMDB information: 83302
• Descriptor: Outward-rectifier potassium channel TOK1, CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: ion channel, k2p, two-pore-domain potassiumu channel, membrane protein
• Biological source: Saccharomyces cerevisiae (brewer's yeast)
• Total number of polymer chains: 2
• Total formula weight: 173462.29

Authors

Sano, F.K.,Yamaguchi, K.,Hashimoto, K.,Sawada, K.,Hirano, H.,Itoh, Y.,Kise, Y.,Nureki, O. (deposition date: 2026-08-30, release date: 2026-09-16)

• Primary citation: Sano, F.K.,Kasuya, G.,Yamaguchi, K.,Suzuki, T.,Hashimoto, K.,Inoue, M.,Sawada, K.,Ishitani, R.,Yoshimura, K.,Hirano, H.,Itoh, Y.,Nakajo, K.,Dohmae, N.,Kise, Y.,Nureki, O.; Structural basis of lipid-mediated gating in a two-pore domain potassium channel TOK1; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.6 Å)