44AC

Crystal structure of FGFR1 with a nucleoside scaffold-based inhibitor LJ5438

This is a non-PDB format compatible entry.

Summary for 44AC

• Entry DOI: 10.2210/pdb44ac/pdb
• Descriptor: Fibroblast growth factor receptor 1, ~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-2-fluoranyl-prop-2-enamide (3 entities in total)
• Functional Keywords: fgfr1, nucleoside scaffold-based inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 70509.17

Authors

Han, B.W.,Ko, H.L. (deposition date: 2026-07-22, release date: 2026-10-14)

• Primary citation: Han, B.W.,Ko, H.L.; Crystal structure of FGFR1 with a nucleoside scaffold-based inhibitor LJ5438; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.97 Å)