44AC
Crystal structure of FGFR1 with a nucleoside scaffold-based inhibitor LJ5438
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Fibroblast growth factor receptor 1 | polymer | 304 | 34741.0 | 2 | UniProt (P11362) Pfam (PF07714) | Homo sapiens (human) | FGFR-1,Basic fibroblast growth factor receptor 1,BFGFR,bFGF-R-1,Fms-like tyrosine kinase 2,FLT-2,N-sam |
| 2 | C, D (A, B) | ~{N}-[[(2~{R},3~{S},4~{R},5~{R})-5-[4-azanyl-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl]-2-fluoranyl-prop-2-enamide | non-polymer | 513.5 | 2 | Chemie (A1MIR) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 310 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69482.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1027.1 | |
| All* | Total formula weight | 70509.2 |
