3ZWY

Crystal structure of ADP-ribosyl cyclase complexed with 8-bromo-ADP- ribose and cyclic 8-bromo-cyclic-ADP-ribose

Summary for 3ZWY

• Entry DOI: 10.2210/pdb3zwy/pdb
• Related: 1LBE 1R0S 1R12 1R15 1R16 3ZWN 3ZWO 3ZWP
• Descriptor: ADP-RIBOSYL CYCLASE, [(2R,3S,4R,5R)-5-(6-amino-8-bromo-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl [(2R,3S,4S)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate, (2R,3R,4S,5R,13R,14S,15R,16R)-24-amino-18-bromo-3,4,14,15-tetrahydroxy-7,9,11,25,26-pentaoxa-17,19,22-triaza-1-azonia-8 ,10-diphosphapentacyclo[18.3.1.1^2,5^.1^13,16^.0^17,21^]hexacosa-1(24),18,20,22-tetraene-8,10-diolate 8,10-dioxide, ... (4 entities in total)
• Functional Keywords: hydrolase, substrate specificity
• Biological source: APLYSIA CALIFORNICA (CALIFORNIA SEA HARE)
• Cellular location: Cytoplasmic vesicle: P29241
• Total number of polymer chains: 8
• Total formula weight: 242753.50

Authors

Kotaka, M.,Graeff, R.,Zhang, L.H.,Lee, H.C.,Hao, Q. (deposition date: 2011-08-03, release date: 2012-08-22, Last modification date: 2023-12-20)

• Primary citation: Kotaka, M.,Graeff, R.,Chen, Z.,Zhang, L.H.,Lee, H.C.,Hao, Q.; Structural Studies of Intermediates Along the Cyclization Pathway of Aplysia Adp-Ribosyl Cyclase.; To be Published,

Experimental method

X-RAY DIFFRACTION (2.4 Å)