3ZOO

Structure of the Y46F mutant of human cytochrome c

Summary for 3ZOO

DescriptorCYTOCHROME C, HEME C, PHOSPHATE ION, ... (4 entities in total)
Functional Keywordsoxidoreductase, respiration, apoptosis, electron transfer
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationMitochondrion intermembrane space P99999
Total number of polymer chains4
Total molecular weight49162.28
Authors
Rajagopal, B.S.,Worrall, J.A.R.,Hough, M.A. (deposition date: 2013-02-22, release date: 2013-10-23, Last modification date: 2015-11-11)
Primary citation
Rajagopal, B.S.,Edzuma, A.N.,Hough, M.A.,Blundell, K.L.I.M.,Kagan, V.E.,Kapralov, A.A.,Fraser, L.A.,Butt, J.N.,Silkstone, G.G.,Wilson, M.T.,Svistunenko, D.A.,Worrall, J.A.R.
The Hydrogen Peroxide Induced Radical Behaviour in Human Cytochrome C Phospholipid Complexes: Implications for the Enhanced Pro-Apoptotic Activity of the G41S Mutant
Biochem.J., 456:441-, 2013
PubMed: 24099549 (PDB entries with the same primary citation)
DOI: 10.1042/BJ20130758
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.35 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.18360.2%2.4%1.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 3zoo
no rotation
Molmil generated image of 3zoo
rotated about x axis by 90°
Molmil generated image of 3zoo
rotated about y axis by 90°
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