3ZON
Human TYK2 pseudokinase domain bound to a kinase inhibitor
Summary for 3ZON
Entry DOI | 10.2210/pdb3zon/pdb |
Descriptor | NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2, 5-PHENYL-2-UREIDOTHIOPHENE-3-CARBOXAMIDE (3 entities in total) |
Functional Keywords | transferase, jak |
Biological source | HOMO SAPIENS (HUMAN) |
Total number of polymer chains | 1 |
Total formula weight | 37667.81 |
Authors | Elkins, J.M.,Wang, J.,Krojer, T.,Savitsky, P.,Chalk, R.,Daga, N.,Salah, E.,Berridge, G.,Picaud, S.,von Delft, F.,Bountra, C.,Edwards, A.,Knapp, S. (deposition date: 2013-02-22, release date: 2013-04-10, Last modification date: 2023-12-20) |
Primary citation | Elkins, J.M.,Wang, J.,Krojer, T.,Savitsky, P.,Chalk, R.,Daga, N.,Salah, E.,Berridge, G.,Picaud, S.,von Delft, F.,Bountra, C.,Edwards, A.,Knapp, S. Human Tyk2 Pseudokinase Domain Bound to a Kinase Inhibitor To be Published, |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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