3ZON

Human TYK2 pseudokinase domain bound to a kinase inhibitor

Summary for 3ZON

• Entry DOI: 10.2210/pdb3zon/pdb
• Descriptor: NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2, 5-PHENYL-2-UREIDOTHIOPHENE-3-CARBOXAMIDE (3 entities in total)
• Functional Keywords: transferase, jak
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 1
• Total formula weight: 37667.81

Authors

Elkins, J.M.,Wang, J.,Krojer, T.,Savitsky, P.,Chalk, R.,Daga, N.,Salah, E.,Berridge, G.,Picaud, S.,von Delft, F.,Bountra, C.,Edwards, A.,Knapp, S. (deposition date: 2013-02-22, release date: 2013-04-10, Last modification date: 2023-12-20)

• Primary citation: Elkins, J.M.,Wang, J.,Krojer, T.,Savitsky, P.,Chalk, R.,Daga, N.,Salah, E.,Berridge, G.,Picaud, S.,von Delft, F.,Bountra, C.,Edwards, A.,Knapp, S.; Human Tyk2 Pseudokinase Domain Bound to a Kinase Inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.15 Å)