3ZON
Human TYK2 pseudokinase domain bound to a kinase inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NON-RECEPTOR TYROSINE-PROTEIN KINASE TYK2 | polymer | 335 | 37406.5 | 1 | UniProt (P29597) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | |
| 2 | B (A) | 5-PHENYL-2-UREIDOTHIOPHENE-3-CARBOXAMIDE | non-polymer | 261.3 | 1 | Chemie (IK1) | |||
| 3 | C (A) | water | water | 18.0 | 123 | Chemie (HOH) |
Sequence modifications
A: 541 - 873 (UniProt: P29597)
| PDB | External Database | Details |
|---|---|---|
| Ser 539 | - | expression tag |
| Met 540 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37406.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 261.3 | |
| All* | Total formula weight | 37667.8 |
