3X1H
hPPARgamma Ligand binding domain in complex with 5-oxo-tricosahexaenoic acid
Summary for 3X1H
Entry DOI | 10.2210/pdb3x1h/pdb |
Related | 3X1I |
Descriptor | Peroxisome proliferator-activated receptor gamma, (7E,11Z,14Z,17Z,20Z)-5-oxotricosa-7,11,14,17,20-pentaenoic acid (3 entities in total) |
Functional Keywords | nuclear receptor, transcription regulation, ligand binding domain, diabetes mellitus, zinc-finger, dna-binding, transcription, obesity |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P37231 |
Total number of polymer chains | 2 |
Total formula weight | 63616.07 |
Authors | Egawa, D.,Itoh, T.,Yamamoto, K. (deposition date: 2014-11-18, release date: 2015-04-08, Last modification date: 2022-08-24) |
Primary citation | Egawa, D.,Itoh, T.,Yamamoto, K. Characterization of covalent bond formation between PPAR gamma and oxo-fatty acids. Bioconjug.Chem., 26:690-698, 2015 Cited by PubMed: 25785518DOI: 10.1021/acs.bioconjchem.5b00021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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