3WSJ
HTLV-1 protease in complex with the HIV-1 protease inhibitor Indinavir
Summary for 3WSJ
Entry DOI | 10.2210/pdb3wsj/pdb |
Related | 3LIX |
Descriptor | Protease, N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, SULFATE ION, ... (5 entities in total) |
Functional Keywords | retroviral protease, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Human T-lymphotropic virus 1 |
Total number of polymer chains | 2 |
Total formula weight | 27189.99 |
Authors | Kuhnert, M.,Steuber, H.,Diederich, W.E. (deposition date: 2014-03-14, release date: 2014-10-22, Last modification date: 2023-11-08) |
Primary citation | Kuhnert, M.,Steuber, H.,Diederich, W.E. Structural basis for HTLV-1 protease inhibition by the HIV-1 protease inhibitor indinavir. J.Med.Chem., 57:6266-6272, 2014 Cited by PubMed: 25006983DOI: 10.1021/jm500402c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.404 Å) |
Structure validation
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