3WSJ
HTLV-1 protease in complex with the HIV-1 protease inhibitor Indinavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 116 | 12566.6 | 2 | UniProt (Q82134) | Human T-lymphotropic virus 1 | |
| 2 | C (A) | N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE | non-polymer | 613.8 | 1 | Chemie (MK1) PubChem (3706) PubChem (60959) PubChem (5742636) PubChem (9830401) PubChem (9830402) PubChem (12087375) PubChem (15297462) PubChem (23351649) PubChem (23351650) PubChem (45357136) PubChem (46930980) PubChem (3033831) PubChem (53713043) PubChem (58611802) PubChem (58648987) PubChem (59968716) PubChem (60944) PubChem (73265189) PubChem (92758843) PubChem (5362440) PubChem (53713044) PubChem (121366818) PubChem (124932813) PubChem (131632872) PubChem (134462109) PubChem (146347456) PubChem (59096995) PubChem (59913783) PubChem (69890555) PubChem (70259941) PubChem (92758844) PubChem (124932812) PubChem (124932814) PubChem (134693149) PubChem (135081786) PubChem (141832585) PubChem (165707142) | |||
| 3 | D, E, F, G, H... (A, B) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 4 | N (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) PubChem (8200) | |||
| 5 | R, S (A, B) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 116 (UniProt: Q82134)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2056.8 | |
| All* | Total formula weight | 27190.0 |
