3WSJ
HTLV-1 protease in complex with the HIV-1 protease inhibitor Indinavir
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Protease | polymer | 116 | 12566.6 | 2 | UniProt (Q82134) Pfam (PF00077) | Human T-lymphotropic virus 1 | |
| 2 | C (A) | N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE | non-polymer | 613.8 | 1 | Chemie (MK1) | |||
| 3 | D, E, F, G, H... (A, B) | SULFATE ION | non-polymer | 96.1 | 13 | Chemie (SO4) | |||
| 4 | N (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | R, S (A, B) | water | water | 18.0 | 68 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 116 (UniProt: Q82134)
| PDB | External Database | Details |
|---|---|---|
| Ile 40 | Leu 40 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25133.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 2056.8 | |
| All* | Total formula weight | 27190.0 |
