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3WPC

Crystal structure of horse TLR9 in complex with agonistic DNA1668_12mer

Summary for 3WPC
Entry DOI10.2210/pdb3wpc/pdb
Related3WPB 3WPD 3WPE 3WPF 3WPG 3WPH 3WPI
DescriptorToll-like receptor 9, DNA (5'-D(*CP*AP*TP*GP*AP*CP*GP*TP*TP*CP*CP*T)-3'), 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
Functional Keywordsleucine rich repeat, receptor, innate immunity, dna binding, glycosylation, dna binding protein-dna complex, dna binding protein/dna
Biological sourceEquus caballus (domestic horse, equine)
More
Total number of polymer chains4
Total formula weight190113.57
Authors
Ohto, U.,Tanji, H.,Shimizu, T. (deposition date: 2014-01-11, release date: 2015-02-11, Last modification date: 2020-07-29)
Primary citationOhto, U.,Shibata, T.,Tanji, H.,Ishida, H.,Krayukhina, E.,Uchiyama, S.,Miyake, K.,Shimizu, T.
Structural basis of CpG and inhibitory DNA recognition by Toll-like receptor 9
Nature, 520:702-705, 2015
Cited by
PubMed: 25686612
DOI: 10.1038/nature14138
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.6 Å)
Structure validation

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