3WJZ
Orotidine 5'-monophosphate decarboxylase D75N mutant from M. thermoautotrophicus complexed with 6-amino-UMP
Summary for 3WJZ
| Entry DOI | 10.2210/pdb3wjz/pdb |
| Related | 3WJW 3WJX 3WJY 3WK0 3WK1 3WK2 3WK3 |
| Descriptor | Orotidine 5'-phosphate decarboxylase, 6-AMINOURIDINE 5'-MONOPHOSPHATE, CHLORIDE ION, ... (5 entities in total) |
| Functional Keywords | protein-ligand complex, tim barrel, decarboxylase, pyrimidine biosynthesis, lyase |
| Biological source | Methanothermobacter thermautotrophicus |
| Total number of polymer chains | 1 |
| Total formula weight | 27937.26 |
| Authors | Fujihashi, M.,Pai, E.F.,Miki, K. (deposition date: 2013-10-17, release date: 2013-12-04, Last modification date: 2023-11-08) |
| Primary citation | Fujihashi, M.,Ishida, T.,Kuroda, S.,Kotra, L.P.,Pai, E.F.,Miki, K. Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135:17432-17443, 2013 Cited by PubMed: 24151964DOI: 10.1021/ja408197k PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.39 Å) |
Structure validation
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