3WK1

Wild-type orotidine 5'-monophosphate decarboxylase from M. thermoautotrophicus complexed with orotidine 5'-monophosphate ethyl ester

Summary for 3WK1

Entry DOI	10.2210/pdb3wk1/pdb
Related	3WJW 3WJX 3WJY 3WK0 3WK2 3WK3 3WKZ
Descriptor	Orotidine 5'-phosphate decarboxylase, 6-(ethoxycarbonyl)uridine 5'-(dihydrogen phosphate), GLYCEROL, ... (4 entities in total)
Functional Keywords	protein-ligand complex, tim barrel, decarboxylase, pyrimidine biosynthesis, lyase
Biological source	Methanothermobacter thermautotrophicus
Total number of polymer chains	1
Total formula weight	27959.83
Authors	Fujihashi, M.,Pai, E.F.,Miki, K. (deposition date: 2013-10-17, release date: 2013-12-04, Last modification date: 2023-11-08)
Primary citation	Fujihashi, M.,Ishida, T.,Kuroda, S.,Kotra, L.P.,Pai, E.F.,Miki, K. Substrate distortion contributes to the catalysis of orotidine 5'-monophosphate decarboxylase. J.Am.Chem.Soc., 135:17432-17443, 2013 Cited by PubMed: 24151964 DOI: 10.1021/ja408197k PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation