3WJ4

Crystal structure of PPARgamma ligand binding domain in complex with tributyltin

Summary for 3WJ4

Related3WJ5
DescriptorPeroxisome proliferator-activated receptor gamma, tributylstannanyl (3 entities in total)
Functional Keywordsprotein-ligand complex, dna-binding, metal-binding, nucleus, receptor, transcription
Biological sourceHomo sapiens (human)
Cellular locationNucleus P37231
Total number of polymer chains2
Total molecular weight63397.04
Authors
Primary citation
Harada, S.,Hiromori, Y.,Fukakusa, S.,Kawahara, K.,Nakamura, S.,Noda, M.,Uchiyama, S.,Fukui, K.,Nishikawa, J.,Nagase, H.,Kobayashi, Y.,Ohkubo, T.,Yoshida, T.,Nakanishi, T.
Structural basis for PPARgamma transactivation by endocrine disrupting organotin compounds
To be Published,
Experimental method
X-RAY DIFFRACTION (1.95 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2401404.8%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report