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3WJ4

Crystal structure of PPARgamma ligand binding domain in complex with tributyltin

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0004879molecular_functionnuclear receptor activity
A0005634cellular_componentnucleus
A0006355biological_processregulation of DNA-templated transcription
B0003677molecular_functionDNA binding
B0004879molecular_functionnuclear receptor activity
B0005634cellular_componentnucleus
B0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues7
DetailsBINDING SITE FOR RESIDUE TBY A 501
ChainResidue
ACYS285
ASER289
ATYR327
AVAL339
APHE363
AMET364
AHIS449

site_idAC2
Number of Residues10
DetailsBINDING SITE FOR RESIDUE TBY B 501
ChainResidue
BARG288
BTYR327
BLEU330
BVAL339
BLEU353
BPHE363
BMET364
BHIS449
BGLY284
BCYS285

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:9744270, ECO:0007744|PDB:2PRG
ChainResidueDetails
AGLN286
AHIS323
AHIS449
ATYR473
BGLN286
BHIS323
BHIS449
BTYR473

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PDB entries from 2024-03-27

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