3W5O

Crystal Structure of Human DNA ligase IV

Summary for 3W5O

Entry DOI	10.2210/pdb3w5o/pdb
Related	1IK9 2E2W 3II6 3VNN 3W1B 3W1G
Descriptor	DNA ligase 4, ADENOSINE-5'-TRIPHOSPHATE, SULFATE ION, ... (4 entities in total)
Functional Keywords	dna ligase, non homologous end joining, dna repair, xrcc4, artemis, ligase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P49917
Total number of polymer chains	2
Total formula weight	142396.50
Authors	Gu, X.,Ochi, T.,Blundell, T.L. (deposition date: 2013-02-02, release date: 2013-04-03, Last modification date: 2023-11-08)
Primary citation	Ochi, T.,Gu, X.,Blundell, T.L. Structure of the catalytic region of DNA ligase IV in complex with an artemis fragment sheds light on double-strand break repair Structure, 21:672-679, 2013 Cited by PubMed: 23523427 DOI: 10.1016/j.str.2013.02.014 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.84 Å)

Structure validation