3W39
Crystal structure of HLA-B*5201 in complexed with HIV immunodominant epitope (TAFTIPSI)
Summary for 3W39
Entry DOI | 10.2210/pdb3w39/pdb |
Descriptor | HLA class I histocompatibility antigen, B-52 alpha chain, Beta-2-microglobulin, peptid from Gag-Pol polyprotein (3 entities in total) |
Functional Keywords | class i major histocompatibility complex, mhc, membrane, immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Membrane; Single-pass type I membrane protein: P30490 Secreted: P61769 Matrix protein p17: Virion (Potential). Capsid protein p24: Virion (Potential). Nucleocapsid protein p7: Virion (Potential). Reverse transcriptase/ribonuclease H: Virion (Potential). Integrase: Virion (Potential): P12499 |
Total number of polymer chains | 6 |
Total formula weight | 89731.51 |
Authors | Yagita, Y.,Kuse, N.,Kuroki, K.,Gatanaga, H.,Carlson, J.M.,Chikata, T.,Brumme, Z.L.,Murakoshi, H.,Akahoshi, T.,Pfeifer, N.,Mallal, S.,John, M.,Ose, T.,Matsubara, H.,Kanda, R.,Fukunaga, Y.,Honda, K.,Kawashima, Y.,Ariumi, Y.,Oka, S.,Maenaka, K.,Takiguchi, M. (deposition date: 2012-12-13, release date: 2013-02-13, Last modification date: 2023-11-08) |
Primary citation | Yagita, Y.,Kuse, N.,Kuroki, K.,Gatanaga, H.,Carlson, J.M.,Chikata, T.,Brumme, Z.L.,Murakoshi, H.,Akahoshi, T.,Pfeifer, N.,Mallal, S.,John, M.,Ose, T.,Matsubara, H.,Kanda, R.,Fukunaga, Y.,Honda, K.,Kawashima, Y.,Ariumi, Y.,Oka, S.,Maenaka, K.,Takiguchi, M. Distinct HIV-1 Escape Patterns Selected by Cytotoxic T Cells with Identical Epitope Specificity J.Virol., 87:2253-2263, 2013 Cited by PubMed: 23236061DOI: 10.1128/JVI.02572-12 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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