3W1B

Crystal Structure of Human DNA ligase IV-Artemis Complex (Mercury Derivative)

Summary for 3W1B

• Entry DOI: 10.2210/pdb3w1b/pdb
• Related: 1IK9 1X9N 2E2W 3II6 3L2P 3VNN 3W1G 3W5O
• Descriptor: DNA ligase 4, Artemis-derived peptide, ADENOSINE MONOPHOSPHATE, ... (6 entities in total)
• Functional Keywords: dna ligase, non-homologous end joining, dna repair, xrcc4, ligase
• Biological source: Homo sapiens (human); More
• Cellular location: Nucleus: P49917 Q96SD1
• Total number of polymer chains: 2
• Total formula weight: 74104.13

Authors

Ochi, T.,Blundell, T.L. (deposition date: 2012-11-14, release date: 2013-04-03, Last modification date: 2013-08-14)

• Primary citation: Ochi, T.,Gu, X.,Blundell, T.L.; Structure of the catalytic region of DNA ligase IV in complex with an artemis fragment sheds light on double-strand break repair; Structure, 21:672-679, 2013; PubMed: 23523427; DOI: 10.1016/j.str.2013.02.014

Experimental method

X-RAY DIFFRACTION (2.4 Å)