3W1A

Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate derivatives

Summary for 3W1A

• Entry DOI: 10.2210/pdb3w1a/pdb
• Descriptor: Dihydroorotate dehydrogenase (fumarate), FLAVIN MONONUCLEOTIDE, COBALT HEXAMMINE(III), ... (6 entities in total)
• Functional Keywords: rossmann fold, oxidoreductase, dihydroorotate/orotate binding, cytosol
• Biological source: Trypanosoma cruzi
• Cellular location: Cytoplasm (By similarity): Q4D3W2
• Total number of polymer chains: 2
• Total formula weight: 70109.02

Authors

Inaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Matsuoka, S.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K. (deposition date: 2012-11-13, release date: 2013-11-13, Last modification date: 2023-11-08)

• Primary citation: Inaoka, D.K.,Iida, M.,Tabuchi, T.,Lee, N.,Matsuoka, S.,Shiba, T.,Sakamoto, K.,Suzuki, S.,Balogun, E.O.,Nara, T.,Aoki, T.,Inoue, M.,Honma, T.,Tanaka, A.,Harada, S.,Kita, K.; Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate derivatives; To be Published,

Experimental method

X-RAY DIFFRACTION (1.42 Å)