3W1A
Structure of Trypanosoma cruzi dihydroorotate dehydrogenase in complex with 5-halogenated orotate derivatives
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Dihydroorotate dehydrogenase (fumarate) | polymer | 313 | 34067.2 | 2 | UniProt (Q4D3W2) Pfam (PF01180) | Trypanosoma cruzi | DHOD, DHODase, DHOdehase, Dihydroorotate oxidase |
| 2 | C, I (A, B) | FLAVIN MONONUCLEOTIDE | non-polymer | 456.3 | 2 | Chemie (FMN) | |||
| 3 | D (A) | COBALT HEXAMMINE(III) | non-polymer | 161.1 | 1 | Chemie (NCO) | |||
| 4 | E, J (A, B) | 5-FLUORO-2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXYLIC ACID | non-polymer | 174.1 | 2 | Chemie (FOT) | |||
| 5 | F, G, H, K, L... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 745 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 68134.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1974.5 | |
| All* | Total formula weight | 70109.0 |
