3W10
Aurora kinase A complexed to pyrazole aminoquinoline I
Summary for 3W10
| Entry DOI | 10.2210/pdb3w10/pdb |
| Related | 3W16 3W18 |
| Descriptor | Aurora kinase A, 1-(3-methoxyphenyl)-N-(5-methyl-1H-pyrazol-3-yl)isoquinolin-3-amine (3 entities in total) |
| Functional Keywords | kinase, pyrazole aminoquinoline, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome: O14965 |
| Total number of polymer chains | 1 |
| Total formula weight | 32485.24 |
| Authors | |
| Primary citation | Oliveira, T.M.,Kairies, N.A.,Engh, R.A. Flexibility and multiple conformations of the activation and glycine rich loops of Aurora A accompanying inhibitor binding To be Published, |
| Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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