3W0R
Crystal structure of a thermostable mutant of aminoglycoside phosphotransferase APH(4)-Ia (N202A), ternary complex with AMP-PNP and hygromycin B
Summary for 3W0R
Entry DOI | 10.2210/pdb3w0r/pdb |
Related | 3W0M 3W0N 3W0O 3W0P 3W0Q 3W0S |
Descriptor | Hygromycin-B 4-O-kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, HYGROMYCIN B VARIANT, ... (4 entities in total) |
Functional Keywords | phosphotransferase, transferase-antibiotic complex, transferase/antibiotic |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 40067.48 |
Authors | Iino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S. (deposition date: 2012-11-02, release date: 2013-08-07, Last modification date: 2024-03-20) |
Primary citation | Iino, D.,Takakura, Y.,Fukano, K.,Sasaki, Y.,Hoshino, T.,Ohsawa, K.,Nakamura, A.,Yajima, S. Crystal structures of the ternary complex of APH(4)-Ia/Hph with hygromycin B and an ATP analog using a thermostable mutant. J.Struct.Biol., 183:76-85, 2013 Cited by PubMed: 23747390DOI: 10.1016/j.jsb.2013.05.023 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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